Sleep affects our thinking. When we get enough sleep, the brain's thinking becomes clear; and when we don't have enough sleep, the brain becomes sluggish.
Recently, the top international magazine "Science" published two consecutive studies revealing that the recovery effect of sleep is related to neuronal activity and synaptic plasticity. New research shows that cells are regularly prepared around synapses in order to build synaptic proteins during sleep. However, when sleep is deprived or jet lag is reversed, neurons will not produce these key proteins, which in turn affects the brain's thinking.
"IQ decline" turned out to be changes in nerve synapses
Synapse is the main mechanism of communication in neural networks. Neurons send signals by releasing neurotransmitters. These neurotransmitters either stimulate downstream neurons or inhibit their firing. Learning and memory depend on changes in synaptic communication, and changes in synaptic communication enable new neural networks to store some information and drive our thinking, emotions and behavior.
Professor Sara B. Noya of the Institute of Pharmacology and Toxicology of the University of Zurich and her colleagues isolated synapses from the forebrain of mice, and then extracted 4,000 different proteins. To determine whether the abundance of these different proteins will change, they sampled every four hours.
Researchers found that 11.7% of synaptic proteins increase or decrease synchronously with the day and night alternation, peaking at dusk and dawn.
lack of sleep breaks the synaptic protein cycle
Sleep deprivation can cause serious mental damage, so will the circadian changes of mRNA and protein molecules be affected by keeping mice awake?
Researchers discovered that the proteins in the synapses of mice with insufficient sleep no longer circulate. Because proteins perform cell activities and synaptic transmission, sleep deprivation can disrupt the normal synaptic protein cycle and impair synaptic function. Although sleep deprivation disrupts the day-night cycle of synaptic proteins, the mRNA molecules that provide the protein to make the protein maintain a daily rhythm, which means that sleep deprivation does not work by impairing the reading of the genetic code. In other words, the production of mRNA has nothing to do with sleep quality, but sleep quality has a great impact on protein levels.
Nowadays, the time and quality of sleep have become the capital for contemporary young people to "show off their wealth". Sleep well and keep your brain awake can learn and work better.